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Scientist - Cell Line Development

South San Francisco - Technology Full-Time
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.  Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.  Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are seeking an organized and motivated Scientist to lead  the Cell Line Generation group. The successful candidate will work closely with project teams to design and generate engineered cell lines in support of preclinical programs.

What You Will Do:

Lead a group of Research Associates that provides centralized support for cell line generation, expansion and QC for projects

Lead the development, application and optimization of new technologies for modifying the genomes of mammalian cells

Employ strategies for the genetic modification of cell linesLead activities in generating and maintaining master and working cell bank inventories across a portfolio of engineered cell linesLead analysis and QC processes on cell lines at the DNA and protein level

Provide expert support for cell line engineering experiment design and assay development to the broader scientific team.

Coordinate tasks across multiple projects, demonstrating prioritization and planning.

Interpret and effectively execute experiments in line with project timelines and goals

Maintain familiarity with current literature related to the scope of ArsenalBio’s research focus

Mentor research associates within the group in areas of technical expertise

What You Will Bring:

PhD in Cell or Molecular Biology, Biological Sciences or a related field, with 3+ years of relevant research experience in industry or academiaExpertise with CRISPR gene editing and lentiviral transduction workflows, cell engineering and cell culture

Experience developing/optimizing gene editing protocols

Experience analyzing mammalian cells by flow cytometry for target surface expression

Experience with Fluorescence-activated cell sorting (FACS)

Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done 

Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results 

Flexible mindset with ability to think outside the box, creative approach to problem solving, and comfort in working with ambiguous data in an open-ended, exploratory process

Demonstrated ability to perform as a team playerStrong organizational skills, record keeping and interpersonal communication skills (verbal and written)

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.