Process Development Scientist (Process Development and Technology Operations)
South San Francisco
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. Our products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments. Our people are our greatest asset, they bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.
We are seeking a talented and motivated Scientist to join the ArsenalBio Process Development team. The individual will work closely with team members to develop GMP-compatible processes and procedures that will lead to the effective manufacture of our cell therapy products. This position will report into the Process Development team lead and aid in the technical development of a GMP-enabling cell therapy manufacturing process. The individual will also interact cross-functionally within Process Development and Tech Ops and across the organization to enable the success of ArsenalBio.
What You Will Do
Plan, execute, analyze, and report on experiments and analytic assays to support the development of a GMP process to manufacture, characterize, and release T cell therapy products.Compile documentation (protocols, batch records, and study reports) to facilitate transfer of ArsenalBio’s process to external CDMO(s)Collaborate closely with other functions to enable effective and successful project executionActively engage in cross-functional collaboration with peers to overcome technical challengesOrganize, communicate, and present complex data sets to key stakeholders and senior managementAssist cross-functional activities including hand-offs to various teams, compiling data, and presenting at project meetings
What You Will Bring
PhD in a relevant scientific discipline (such as Biotechnology, Bioprocess engineering, Immunology, Molecular Biology, or Biochemistry)Expertise in clinical scale human immune cell isolation, T cell expansion, and mammalian cell culture techniques required2+ years of relevant research experience in T cell biology and/or immunotherapy preferred Prior experience in cell therapy and/or process development teams preferredExpertise in multi-color flow cytometry analyses including panel design and data analysis requiredUnderstanding of cGMP environment, Design of Experiment (DOE), and Quality by Design (QBD) principles for process and assay development, qualification, and validation preferredExperience in harvest, fill, finish and evaluation of cryopreservation techniques preferredExperience in T cell functional assays including cytotoxicity, cytokine/chemokine, and proliferation a plus Ability to quickly adapt and learn new skills for changing research prioritiesFlexible mind with the ability to think outside the box, creative approach to problem-solvingDemonstrated ability to work well in a highly collaborative team environment, coordinate tasks across multiple projects to meet deadlinesWillingness to accept other responsibilities outside of initial job description
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status
To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or Arsenalbio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.